Marcela Moncada‐Vélez

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Jérémie Rosain et al. · Science Immunology · 2021 · 631 citations · Full text

Life Sciences, Immunology, Infectious Diseases +11

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi et al. · Science Immunology · 2021 · 420 citations · Full text

Life Sciences, Immunology, Molecular Genetics +14

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

Alexandra Y. Kreins, Michael J. Ciancanelli, Satoshi Okada et al. · The Journal of Experimental Medicine · 2015 · 356 citations

Life Sciences, Dermatology, Immunology +17

The human gene damage index as a gene-level approach to prioritizing exome variants

Yuval Itan, Lei Shang, Bertrand Boisson et al. · Proceedings of the National Academy of Sciences · 2015 · 279 citations · Full text

Life Sciences, Bioinformatics, Genetics +17