Michael J. Pattison

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway

Kirsty F. MacKenzie, Kristopher Clark, Shaista Naqvi et al. · The Journal of Immunology · 2012 · 236 citations · Full text

Inhibition of JAKs in Macrophages Increases Lipopolysaccharide-Induced Cytokine Production by Blocking IL-10–Mediated Feedback

Michael J. Pattison, Kirsty F. MacKenzie, J. Simon C. Arthur · The Journal of Immunology · 2012 · 126 citations · Full text

Jak/stat3-dependent Pathway, Immunology, Immune Regulation +20

Development of Selective Covalent Janus Kinase 3 Inhibitors

Li Tan, Koshi Akahane, Randall McNally et al. · Journal of Medicinal Chemistry · 2015 · 112 citations · Full text

TLR and TNF-R1 activation of the MKK3/MKK6–p38α axis in macrophages is mediated by TPL-2 kinase

Michael J. Pattison, Olivia Mitchell, Helen R. Flynn et al. · Biochemical Journal · 2016 · 60 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +24

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

Jonathan M. Elkins, Jing Wang, Xianming Deng et al. · Journal of Medicinal Chemistry · 2013 · 35 citations · Full text

X-ray Crystallography, Specific Inhibitor, Crystal Structure +20