Christopher J. Creighton

Author

Johnson & Johnson (United States)

Also Known As

Christopher J Creighton, Christopher J. Creighton

Publications

643

Citations

H-Index

Concepts

All Affiliations

Johnson & Johnson (United States)University of California San Diego Ikerbasque Hamari Chemicals (Japan)Lawrence Livermore National Laboratory

About

Christopher J. Creighton is an author at Johnson & Johnson (United States) specializing in natural sciences, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	10	10	507
2	Biochemistry	10	10	495
3	Medicine	7	7	342
4	Biomolecular Engineering	5	5	189
5	Engineering	4	4	146

Christopher J. Creighton

Publications

608

Citations

H-Index

Page 1

	Year	Citations
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity Leslie W. Tari, Michael Trzoss, Daniel C. Bensen, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryDrug TargetDna Gyrase BBiochemistryNatural Sciences	2012	115
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity Micheal Trzoss, Daniel C. Bensen, Xiaoming Li, Bioorganic & Medicinal Chemistry Letters Inhibitory ActivityBiochemistryMedicineNatural SciencesBroad Spectrum	2012	80
Synthesis of an Eight-Membered Cyclic Pseudo-Dipeptide Using Ring Closing Metathesis Christopher J. Creighton, Allen B. Reitz Organic Letters Medicinal ChemistryConstrained ScaffoldBioorganic ChemistryEngineeringBiochemistry	2001	72
Design, synthesis, and conformational analysis of eight-membered cyclic peptidomimetics prepared using ring closing metathesis Christopher J. Creighton, Gregory C. Leo, Yanming Du, Bioorganic & Medicinal Chemistry Combinatorial ChemistryMedicinal ChemistryNovel OrganocatalystsHeterocyclicAlkene Metathesis	2004	55
Scale-up Synthesis of (<i>R</i>)- and (<i>S</i>)-<i>N</i>-(2-Benzoyl-4-chlorophenyl)-1-(3,4-dichlorobenzyl)pyrrolidine-2-carboxamide Hydrochloride, A Versatile Reagent for the Preparation of Tailor-Made α- and β-Amino Acids in an Enantiomerically Pure Form Todd T. Romoff, Andrew B. Palmer, Noel Mansour, Organic Process Research & Development Scale-up Synthesisβ-Amino AcidsA Versatile ReagentBiochemistryMedicine	2017	43
Conformational Analysis of the Eight-Membered Ring of the Oxidized Cysteinyl-Cysteine Unit Implicated in Nicotinic Acetylcholine Receptor Ligand Recognition Christopher J. Creighton, Charles H. Reynolds, Daniel H. S. Lee, Journal of the American Chemical Society Molecular BiologyChemical BiologyPreferred ConformationsNicotinic Acetylcholine ReceptorsMolecular Recognition	2001	39
Mechanistic Studies of an Unusual Amide Bond Scission Christopher J. Creighton, Todd T. Romoff, Jane H. Bu, Journal of the American Chemical Society Mechanistic StudiesCleavage ReactionAmino AcidBiochemistryNmeaib Residue	1999	35
Solid-Phase Synthesis of Pyridones and Pyridopyrazines as Peptidomimetic Scaffolds Christopher J. Creighton, Christoph W. Zapf, Jane H. Bu, Organic Letters Combinatorial ChemistryMedicinal ChemistrySolid PhaseSolid-phase SynthesisHeterocyclic	1999	33
A Novel Traceless Resin-Bound Guanidinylating Reagent for Secondary Amines To Prepare <i>N</i>,<i>N</i>-Disubstituted Guanidines Christoph W. Zapf, Christopher J. Creighton, Mika Tomioka, Organic Letters	2001	30
Noncovalent Self-Assembly of Bicyclo[4.2.2]diketopiperazines: Influence of Saturation in the Bridging Carbacyclic Ring Yanming Du, Christopher J. Creighton, Brett A. Tounge, Organic Letters Noncovalent Self-assemblySupramolecular AssemblyEngineeringHeterocyclicBridging Carbacyclic Tether	2004	28

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