Autophagy Induction by the Pathogen Receptor CD46

Pierre-Emmanuel Joubert, Grégory Meiffren, Isabel Pombo Grégoire, +10

Cell Host & Microbe

Cell AutophagyMitophagyAutoimmune DiseaseAutophagy InductionImmunology +7

Chikungunya virus–induced autophagy delays caspase-dependent cell death

Pierre-Emmanuel Joubert, Scott Werneke, Claire de la Calle, +7

The Journal of Experimental Medicine

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

Isabel Pombo Grégoire, Clémence Richetta, Laurène Meyniel‐Schicklin, +17

PLoS Pathogens

Viral ReplicationGeneticsImmunologyViral PathogenesisVirus-induced Autophagy +17

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

Adrien Decque, Olivier Joffre, João G. Magalhães, +11

Nature Immunology

Innate SensingMolecular PhysiologySignal TransductionMolecular PathwayProtein Expression +8

Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions

Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, +18

Journal for ImmunoTherapy of Cancer

Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses

Brian Webster, Scott Werneke, Biljana Zafirova, +10

eLife

ImmunologyImmunologic MechanismInnate ImmunityImmunotherapyArbovirus +14

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

Pierre-Emmanuel Joubert, Kenneth A. Stapleford, Florence Guivel‐Benhassine, +3

PLoS Pathogens

Viral ReplicationMolecular RegulationImmunologyViral PathogenesisMolecular Biology +21

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

Pierre-Emmanuel Joubert, Scott Werneke, Claire de la Calle, +7

Autophagy

MitophagyLipid PeroxidationApoptosisImmunologyViral Pathogenesis +23

Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

Marion Dajon, Kristina Iribarren, Florent Petitprez, +12

OncoImmunology

Tlr7 StimulationGene Expression SignatureCancer ImmunosurveillanceMalignant CellsMedicine +11

Pathogen recognition by the cell surface receptor CD46 induces autophagy

Grégory Meiffren, Pierre-Emmanuel Joubert, Isabel Pombo Grégoire, +3

Autophagy

InflammationCell AutophagyHost ResponsePathogen RecognitionAutoimmune Disease +13