Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

David Sancho, Olivier Joffre, Anna M. Keller, +5

Nature

InflammationAutoimmune DiseaseAllergyImmunologyAutoimmunity +8

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8α+ dendritic cells

Lionel Franz Poulin, Mariolina Salio, Emmanuel Griessinger, +14

The Journal of Experimental Medicine

Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes

Olivier Joffre, Thibault Santolaria, Denis Calise, +4

Nature Medicine

Transplant RejectionChronic Allograft RejectionCell TherapyTransplantationAutoimmune Disease +8

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

David Sancho, Diego Mourão‐Sá, Olivier Joffre, +5

Journal of Clinical Investigation

Cd8alpha+ DcsImmunologyImmunologic MechanismImmunotherapyTumor Biology +17

Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors

Nicolas Thiault, Julie Darrigues, Véronique Adoue, +9

Nature Immunology

Developmental BiologyAutoimmune DiseaseLymphocyte DevelopmentCell SignalingT-regulatory Cell +9

Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes

Olivier Joffre, Nathalie Gorsse, Paola Romagnoli, +2

Blood

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

Adrien Decque, Olivier Joffre, João G. Magalhães, +11

Nature Immunology

Innate SensingMolecular PhysiologySignal TransductionMolecular PathwayProtein Expression +8

Efficient and versatile manipulation of the peripheral CD4⁺ T‐cell compartment by antigen targeting to DNGR‐1/CLEC9A

Olivier Joffre, David Sancho, Santiago Zelenay, +2

European Journal of Immunology

Adaptive Immune SystemImmunologyMolecular BiologyImmunologic MechanismAntigen Processing +18

The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses

Véronique Adoue, Bénédicte Binet, Agathe Malbec, +5

Immunity

ChromatinChromatin RemodelingEpigenetic ChangeGeneticsHuman Retrovirus +6

TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

Andrea Pichler, Nadège Carrié, Marine Cuisinier, +23

Immunity