Susan D. Orwig

Structural basis for misfolding in myocilin-associated glaucoma

Rebecca K. Donegan, Shannon E. Hill, Dana M. Freeman et al. · Human Molecular Genetics · 2014 · 85 citations · Full text

Protein Assembly, Molecular Biology, Analytical Ultracentrifugation +19

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

Melissa Landon, Raquel L. Lieberman, Quyen Q. Hoang et al. · Journal of Computer-Aided Molecular Design · 2009 · 82 citations · Full text

Protein Chemistry, Protein Assembly, Biochemistry +11

Amyloid Fibril Formation by the Glaucoma-Associated Olfactomedin Domain of Myocilin

Susan D. Orwig, Christopher W. Perry, Laura Y. Kim et al. · Journal of Molecular Biology · 2011 · 59 citations

Alzheimer's Disease, Molecular Biology, Protein Misfolding +4

Rescue of Glaucoma-Causing Mutant Myocilin Thermal Stability by Chemical Chaperones

J. Nicole Burns, Susan D. Orwig, Julia Harris et al. · ACS Chemical Biology · 2010 · 56 citations

Biophysical Characterization of the Olfactomedin Domain of Myocilin, an Extracellular Matrix Protein Implicated in Inherited Forms of Glaucoma

Susan D. Orwig, Raquel L. Lieberman · PLoS ONE · 2011 · 39 citations · Full text