Melissa Landon

Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

Ryan Brenke, Dima Kozakov, Gwo‐Yu Chuang et al. · Bioinformatics · 2009 · 457 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

Identification of Hot Spots within Druggable Binding Regions by Computational Solvent Mapping of Proteins

Melissa Landon, David R. Lancia, Jessamin Yu et al. · Journal of Medicinal Chemistry · 2007 · 128 citations

Pharmacy, Biochemistry, Bioinformatics +11

A Potent, Selective and Cell‐Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

H. Ümit Kanıskan, Magdalena M. Szewczyk, Zhengtian Yu et al. · Angewandte Chemie International Edition · 2015 · 127 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Novel Druggable Hot Spots in Avian Influenza Neuraminidase H5N1 Revealed by Computational Solvent Mapping of a Reduced and Representative Receptor Ensemble

Melissa Landon, Rommie E. Amaro, Riccardo Baron et al. · Chemical Biology & Drug Design · 2008 · 101 citations

Life Sciences, Bioinformatics, Molecular Biology +17

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

Melissa Landon, Raquel L. Lieberman, Quyen Q. Hoang et al. · Journal of Computer-Aided Molecular Design · 2009 · 82 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15