J. Carl Barrett

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +10

Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity

Keith R. Martin, J. Carl Barrett · Human & Experimental Toxicology · 2002 · 362 citations · Full text

Double-edged Swords, Cell Death, Reactive Oxygen Species +18

Evidence for the progressive nature of neoplastic transformation in vitro.

J. Carl Barrett, Paul O. P. Ts’o · Proceedings of the National Academy of Sciences · 1978 · 314 citations · Full text

Pathology, Cell Culture, Cell Proliferation +17

Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines.

Jayne C. Boyer, Asad Umar, John I. Risinger et al. · PubMed · 1995 · 301 citations

Cancer Pathology, Genetics, Pathology +16

The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts.

Alexandra Vaisman, Maria Varchenko, Asad Umar et al. · PubMed · 1998 · 298 citations

Cisplatin Resistance, Chromatin, Genome Instability +15