Graeme E. Walker

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

Sonya Zabludoff, Chun Deng, Michael Grondine et al. · Molecular Cancer Therapeutics · 2008 · 410 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Trans-Spectral Orbital Angular Momentum Transfer via Four-Wave Mixing in Rb Vapor

Graeme E. Walker, Aidan S. Arnold, Sonja Franke‐Arnold · Physical Review Letters · 2012 · 252 citations · Full text

Natural Sciences, Physics, Optics +13

Antiestrogen Therapy Is Active in Selected Ovarian Cancer Cases: The Use of Letrozole in Estrogen Receptor–Positive Patients

John F. Smyth, Charlie Gourley, Graeme E. Walker et al. · Clinical Cancer Research · 2007 · 190 citations · Full text

Medicine, Oncology, Pharmacology +17

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i> -Mutant Breast Tumors in Preclinical Models

Hazel M. Weir, Robert H. Bradbury, Mandy Lawson et al. · Cancer Research · 2016 · 174 citations

Medicine, Oncology, Pharmacology +16

Optimization of a Novel Binding Motif to (<i>E</i>)-3-(3,5-Difluoro-4-((1<i>R</i>,3<i>R</i>)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1<i>H</i>-pyrido[3,4-<i>b</i>]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist

Chris De Savi, Robert H. Bradbury, Alfred A. Rabow et al. · Journal of Medicinal Chemistry · 2015 · 160 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17