Laurence H. Hurley

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Publications

Citations

224

H-Index

Active since

1987

Affiliations

The University of Texas at Austin(Current)

Dynamique du noyau

Laurence H. Hurley is an author at The University of Texas at Austin specializing in molecular biology, medicinal chemistry, and dna adduct formation.

Publications per year

1987–1994

Publications

Structure of the altromycin B (N7-guanine)-DNA adduct. A proposed prototypic DNA adduct structure for the pluramycin antitumor antibiotics

Daekyu Sun, Mark R. Hansen, Jacob J. Clement et al. · Biochemistry · 1993 · 62 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +12

Comparison of a DSB-120 DNA Interstrand Cross-Linked Adduct with the Corresponding Bis-tomaymycin Adduct: An Example of a Successful Template-Directed Approach to Drug Design Based upon the Monoalkylating Compound Tomaymycin

John A. Mountzouris, Jeh‐Jeng Wang, David E. Thurston et al. · Journal of Medicinal Chemistry · 1994 · 47 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice

Paul A. Aristoff, Paul D. Johnson, Daekyu Sun et al. · Journal of Medicinal Chemistry · 1993 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Demonstration of the asymmetric effect of CC-1065 on local DNA structure using a site-directed adduct in a 117-base-pair fragment from M13mp1.

Laurence H. Hurley, Donald R. VanDevanter, C. S. Lee · Proceedings of the National Academy of Sciences · 1987 · 32 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Structure-activity relationships of (+)-CC-1065 analogs in the inhibition of helicase-catalyzed unwinding of duplex DNA

Daekyu Sun, Laurence H. Hurley · Journal of Medicinal Chemistry · 1992 · 26 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

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