John Matson

Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy

Marco A. Passini, Jie Bu, Amy M. Richards et al. · Science Translational Medicine · 2011 · 553 citations · Full text

Medicine, Neurobiology, Neuroscience +12

Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

Frank Rigo, Seung Chun, Daniel A. Norris et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 275 citations · Full text

Medicine, Neuroscience, Pharmacology +14

Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment

Daniel M. Ramos, Constantin d’Ydewalle, Vijayalakshmi Gabbeta et al. · Journal of Clinical Investigation · 2019 · 193 citations · Full text

Medicine, Neurology, Neuroscience +17

PHARMACOKINETICS OF A TUMOR NECROSIS FACTOR-α PHOSPHOROTHIOATE 2′-O-(2-METHOXYETHYL) MODIFIED ANTISENSE OLIGONUCLEOTIDE: COMPARISON ACROSS SPECIES

Richard S. Geary, Rosie Z. Yu, Tanya Watanabe et al. · Drug Metabolism and Disposition · 2003 · 162 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

Elizabeth J. Ackermann, Shuling Guo, Merrill D. Benson et al. · Amyloid · 2016 · 138 citations

Life Sciences, Molecular Biology, Pharmacology +16