Kevin Hudson

Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B α

Kay S. Walker, Mária Deák, Andrew D. Paterson et al. · Biochemical Journal · 1998 · 280 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS

Sarah J. Ross, Alexey S. Revenko, Lyndsey Hanson et al. · Science Translational Medicine · 2017 · 182 citations

Medicine, Oncology, Pharmacology +16

Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation

Richard A. Ward, C. Brassington, Alexander L. Breeze et al. · Journal of Medicinal Chemistry · 2012 · 169 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL

Tabea Erdmann, Pavel Klener, James T. Lynch et al. · Blood · 2017 · 105 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Phase I study of monoclonal antibody-ricin A chain immunotoxin XomaZyme-791 in patients with metastatic colon cancer.

Vera S. Byers, Robert Rodvien, Kathleen A. Grant et al. · PubMed · 1989 · 90 citations

Medicine, Oncology, Pharmacology +11