Shinobu Kitazume

Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

Shinobu Kitazume, Yuriko Tachida, Ritsuko Oka et al. · Proceedings of the National Academy of Sciences · 2001 · 272 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa et al. · EMBO Molecular Medicine · 2015 · 181 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC

Kazuki Nakajima, Shinobu Kitazume, Takashi Angata et al. · Glycobiology · 2010 · 150 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete the O-Glycosylated Form

Shinobu Kitazume, Yuriko Tachida, Masaki Kato et al. · Journal of Biological Chemistry · 2010 · 119 citations · Full text

Life Sciences, Biochemistry, Neuroscience +16

Characterization of α2,6-Sialyltransferase Cleavage by Alzheimer's β-Secretase (BACE1)

Shinobu Kitazume, Yuriko Tachida, Ritsuko Oka et al. · Journal of Biological Chemistry · 2003 · 109 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12