Germinal Center Marker GL7 Probes Activation-Dependent Repression of <i>N</i> -Glycolylneuraminic Acid, a Sialic Acid Species Involved in the Negative Modulation of B-Cell Activation

Yuko Naito, Hiromu Takematsu, Susumu KOYAMA, +12

Molecular and Cellular Biology

An aberrant sugar modification of <scp>BACE</scp> 1 blocks its lysosomal targeting in <scp>A</scp> lzheimer's disease

Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, +12

EMBO Molecular Medicine

Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC

Kazuki Nakajima, Shinobu Kitazume, Takashi Angata, +4

Glycobiology

A Single Dose of Lipopolysaccharide into Mice with Emphysema Mimics Human Chronic Obstructive Pulmonary Disease Exacerbation as Assessed by Micro-Computed Tomography

Satoshi Kobayashi, Reiko Fujinawa, Fumi Ota, +13

American Journal of Respiratory Cell and Molecular Biology

InflammationAsthmaInflammatory CellsAllergyInflammatory Lung Disease +11

Ngly1 −/− rats develop neurodegenerative phenotypes and pathological abnormalities in their peripheral and central nervous systems

Makoto Asahina, Reiko Fujinawa, Sayuri Nakamura, +3

Human Molecular Genetics

Central Nervous SystemsSynaptic SignalingCellular PhysiologySocial SciencesTranscriptional Regulation +22

The Absence of Core Fucose Up-regulates GnT-III and Wnt Target Genes

Ayako Kurimoto, Shinobu Kitazume, Yasuhiko Kizuka, +7

Journal of Biological Chemistry

Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling

Junko Iijima, Satoshi Kobayashi, Shinobu Kitazume, +9

Glycobiology

InflammationToll-like ReceptorsMolecular ImmunologyCore FucosylationImmunology +12

Loss of peptide: <i>N</i> -glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase

Yukiko Yoshida, Makoto Asahina, Arisa Murakami, +8

Proceedings of the National Academy of Sciences

In vivo role of aldehyde reductase

Motoko Takahashi, Satoshi Miyata, Junichi Fujii, +14

Biochimica et Biophysica Acta (BBA) - General Subjects

Aldehyde ReductaseAldo-keto ReductaseAldehyde DehydrogenaseBiochemistryCarbonyl Metabolism +3

α1,6-Fucosyltransferase (Fut8) is implicated in vulnerability to elastase-induced emphysema in mice and a possible non-invasive predictive marker for disease progression and exacerbations in chronic obstructive pulmonary disease (COPD)

Koichiro Kamio, Takayuki Yoshida, Congxiao Gao, +14

Biochemical and Biophysical Research Communications

InflammationAllergyDisease ProgressionAdvanced Lung DiseaseImmunology +5