Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

Shinobu Kitazume, Yuriko Tachida, Ritsuko Oka, +3

Proceedings of the National Academy of Sciences

Characterization of Mouse ST8Sia II (STX) as a Neural Cell Adhesion Molecule-specific Polysialic Acid Synthase

Naoya Kojima, Yuriko Tachida, Yukiko Yoshida, +1

Journal of Biological Chemistry

Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete the O-Glycosylated Form

Shinobu Kitazume, Yuriko Tachida, Masaki Kato, +8

Journal of Biological Chemistry

Protein SecretionGlycobiologyO-glycosylated FormAmyloid Precursor ProteinNeuroinflammation +17

Characterization of α2,6-Sialyltransferase Cleavage by Alzheimer's β-Secretase (BACE1)

Shinobu Kitazume, Yuriko Tachida, Ritsuko Oka, +7

Journal of Biological Chemistry

In Vivo Cleavage of α2,6-Sialyltransferase by Alzheimer β-Secretase

Shinobu Kitazume, Kazuhiro Nakagawa, Ritsuko Oka, +11

Journal of Biological Chemistry

Interleukin‐1β up‐regulates TACE to enhance α‐cleavage of APP in neurons: resulting decrease in Aβ production

Yuriko Tachida, Kazuhiro Nakagawa, Takashi Saito, +9

Journal of Neurochemistry

A CRISPR Screen Identifies LAPTM4A and TM9SF Proteins as Glycolipid-Regulating Factors

Toshiyuki Yamaji, Tsuyoshi Sekizuka, Yuriko Tachida, +4

iScience

GeneticsGlycobiologyCell DeathMolecular GeneticsTranscriptional Regulation +17

Soluble Amyloid Precursor Protein 770 Is Released from Inflamed Endothelial Cells and Activated Platelets

Shinobu Kitazume, Akiomi Yoshihisa, Takayoshi Yamaki, +14

Journal of Biological Chemistry

Biosynthesis and Expression of Polysialic Acid on the Neural Cell Adhesion Molecule Is Predominantly Directed by ST8Sia II/STX during in Vitro Neuronal Differentiation

Naoya Kojima, Mari Kono, Yukiko Yoshida, +3

Journal of Biological Chemistry

Polysialic AcidPathologySt8sia IiCellular PhysiologyEpendyma +15

Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

Antonio Galeone, Joshua Adams, Shinya Matsuda, +11

eLife