Concepedia

Author

Raviraj Kulathila

Novartis (United States)

Also Known As

R. Kulathila, Raviraj KULATHILA, Raviraj Kulathila

36

Publications

1.3K

Citations

19

H-Index

36

Concepts

All Affiliations

Novartis (United States)Medigene (Germany)Duquesne UniversityEmmanuel College - MassachusettsNovartis (Switzerland)
RK

About

Raviraj Kulathila is an author at Novartis (United States) specializing in natural sciences, biochemistry, and chemical biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Natural Sciences

12

12

697

2

Biochemistry

12

12

489

3

Medicine

6

6

469

4

Biomolecular Engineering

6

6

242

5

Engineering

2

2

107

Raviraj Kulathila

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20

Publications

1.1K

Citations

17

H-Index

YearCitations

Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers

Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair,

Journal of Medicinal Chemistry

2018

225

Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor

Young Shin Cho, Julian Levell, Gang Liu,

ACS Medicinal Chemistry Letters

2017

113

<i>N</i>-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity

C J Hackbarth, Dawn Z. Chen, Jason G. Lewis,

Antimicrobial Agents and Chemotherapy

2002

108

Structural Investigations on the Coordination Environment of the Active-Site Copper Centers of Recombinant Bifunctional Peptidylglycine α-Amidating Enzyme

John S. Boswell, Brian Reedy, Raviraj Kulathila,

Biochemistry

1996

90

The Role of the Acidity of N-Heteroaryl Sulfonamides as Inhibitors of Bcl-2 Family Protein–Protein Interactions

B. Barry Touré, Karen Miller‐Moslin, Naeem Yusuff,

ACS Medicinal Chemistry Letters

2013

72

Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity

Xiaoling Xie, Daniel Baird, Kimberly Elizabeth Bowen,

Structure

2017

66

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

Lauren G. Monovich, Rubén Tommasi, Roger A. Fujimoto,

Journal of Medicinal Chemistry

2009

56

Bifunctional Peptidylglycine α-Amidating Enzyme Requires 2 Copper Atoms for Maximum Activity

Raviraj Kulathila, Angelo P. Consalvo, Paul F. Fitzpatrick,

Archives of Biochemistry and Biophysics

1994

56

Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1

Julian Levell, Thomas R. Caferro, Gregg Chenail,

ACS Medicinal Chemistry Letters

2016

44

Oxygen-18 isotopic carbon-13 NMR shift as proof that bifunctional peptidylglycine .alpha.-amidating enzyme is a monooxygenase

David J. Merkler, Raviraj Kulathila, Angelo P. Consalvo,

Biochemistry

1992

38

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