Insup Choi

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration

Insup Choi, Yuanxi Zhang, Steven P. Seegobin et al. · Nature Communications · 2020 · 510 citations · Full text

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence

Insup Choi, Minghui Wang, Seungyeul Yoo et al. · Nature Cell Biology · 2023 · 170 citations · Full text

Cell Autophagy, Alzheimer's Disease, Prevents Microglial Senescence +11

LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Insup Choi, Beomsue Kim, Ji-Won Byun et al. · Nature Communications · 2015 · 114 citations · Full text

Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice

Véronik Lachance, Qian Wang, Eric S. Sweet et al. · Molecular Neurodegeneration · 2019 · 95 citations · Full text

Pink1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced akt and increased p38 mapk activation, and downregulation of egfr

Insup Choi, Jun Kim, Hey‐Kyeong Jeong et al. · Glia · 2013 · 89 citations · Full text

Pink1 Deficiency, Mitophagy, Pink1-ko Astrocytes +13