Cheryl Chan

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 783 citations · Full text

Engineered Fc Regions, Novel Therapy, Antibody Fc Variants +13

Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants

Paul M. Steed, Malú G. Tansey, Jonathan Zalevsky et al. · Science · 2003 · 257 citations

Immunology, Cell Death, Pathology +18

A Novel TLR4-Mediated Signaling Pathway Leading to IL-6 Responses in Human Bladder Epithelial Cells

Jeongmin Song, Matthew J. Duncan, Guojie Li et al. · PLoS Pathogens · 2007 · 176 citations · Full text

Mast Cells Augment Adaptive Immunity by Orchestrating Dendritic Cell Trafficking through Infected Tissues

Christopher P. Shelburne, Hideki Nakano, Ashley L. St. John et al. · Cell Host & Microbe · 2009 · 138 citations · Full text

Inflammation, Autoimmune Disease, Adaptive Immune System +11

Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids

Xiaolin Wu, Joshua K. Tay, Chuan Keng Goh et al. · Biomaterials · 2021 · 104 citations · Full text

Engineering, Nucleic Acid Biomarkers, Genetics +11