Andrew I. Webb

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

Linear ubiquitination prevents inflammation and regulates immune signalling

Björn Gerlach, Stefanie M. Cordier, Anna C. Schmukle et al. · Nature · 2011 · 912 citations

Inflammation, Immunology, Immune Regulation +5

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 581 citations · Full text

CIS is a potent checkpoint in NK cell–mediated tumor immunity

Rebecca B. Delconte, Tatiana B. Kolesnik, Laura F. Dagley et al. · Nature Immunology · 2016 · 373 citations

Cancer Immunosurveillance, Immunology, Tumor Immunity +5

Detection of T790M, the Acquired Resistance <i>EGFR</i> Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

Tilak Sundaresan, Lecia V. Sequist, John V. Heymach et al. · Clinical Cancer Research · 2015 · 343 citations · Full text