U R Rapp

Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.

Deborah K. Morrison, David R. Kaplan, U R Rapp et al. · Proceedings of the National Academy of Sciences · 1988 · 457 citations · Full text

Immunology, Cell Proliferation, Cellular Physiology +19

Mutational activation of c-raf-1 and definition of the minimal transforming sequence.

Gisela Heidecker, M Huleihel, J L Cleveland et al. · Molecular and Cellular Biology · 1990 · 152 citations

Mutant Raf Genes, Genetics, Molecular Biology +16

Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl.

John L. Cleveland, Michael Dean, Naomi Rosenberg et al. · Molecular and Cellular Biology · 1989 · 130 citations · Full text

Hematological Malignancy, Signal Transduction, C-myc Transcription +15

Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor.

Harald App, Ronen Hazan, Asher Zilberstein et al. · Molecular and Cellular Biology · 1991 · 117 citations · Full text

Egf Signal Transduction, Epidermal Growth Factor, Developmental Biology +14

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene.

Mahmoud Huleihel, M Goldsborough, John L. Cleveland et al. · Molecular and Cellular Biology · 1986 · 74 citations

Genetics, Molecular Biology, Molecular Genetics +17