Nicole M. Desforges

Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance

Irina Lonskaya, Michaeline Hebron, Nicole M. Desforges et al. · Journal of Molecular Medicine · 2013 · 155 citations

Cell Autophagy, Alzheimer's Disease, Molecular Neuroscience +10

Tyrosine kinase inhibition increases functional parkin‐ <scp>B</scp> eclin‐1 interaction and enhances amyloid clearance and cognitive performance

Irina Lonskaya, Michaeline Hebron, Nicole M. Desforges et al. · EMBO Molecular Medicine · 2013 · 138 citations · Full text

Cell Death, Synaptic Signaling, Social Sciences +19

Diminished Parkin Solubility and Co-Localization with Intraneuronal Amyloid-β are Associated with Autophagic Defects in Alzheimer's Disease

Irina Lonskaya, Ashot R. Shekoyan, Michaeline Hebron et al. · Journal of Alzheimer s Disease · 2012 · 91 citations

Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance

Irina Lonskaya, Nicole M. Desforges, Michaeline Hebron et al. · PLoS ONE · 2013 · 86 citations · Full text

Mitophagy, Cell Death, Parkin Activity +22

Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease

Irina Lonskaya, Michaeline Hebron, Norah K. Algarzae et al. · Neuroscience · 2012 · 66 citations

Parkin Solubility, Neurodegenerative Diseases, Cell Autophagy +7