Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Thomas Sécher, Sahar Kassem, Mehdi Benamar, +5

Frontiers in Immunology

Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity

Jacob Turner, Emmanuel Stephen‐Victor, Sen Wang, +20

Immunity

AllergyAutoimmune DiseaseAllergy MedicineT-regulatory CellImmune Regulation +8

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

Hani Harb, Mehdi Benamar, Peggy S. Lai, +29

Immunity

InflammationInflammatory Lung DiseaseLung InflammationT-regulatory CellImmunology +6

A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma

Hani Harb, Emmanuel Stephen‐Victor, Elena Crestani, +14

Nature Immunology

InflammationAsthmaImmune Cell DevelopmentT-regulatory CellImmune Regulation +8

Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations

David Zemmour, Louis‐Marie Charbonnier, Juliette Léon, +17

Nature Immunology

Mice UnmasksAutoimmune DiseaseLymphocyte DevelopmentFoxp3 DeficienciesMedicine +9

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes

Caroline Stienne, Michaël F. Michieletto, Mehdi Benamar, +9

Immunity

GeneticsPathogenesisGenomic MechanismGene RegulationMolecular Genetics +5

Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6

Mehdi Benamar, Qian Chen, Mehmet Cihangir Çatak, +17

Journal of Allergy and Clinical Immunology

Function MutationAutoimmune DiseaseAllergyTranscription Factor Stat6Genetics +10

Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

Valentina Poli, Victor Pui‐Yan, Marco Di Gioia, +8

iScience

Smooth muscle cells-derived CXCL10 prevents endothelial healing through PI3Kγ-dependent T cells response

Adrien Lupieri, Natalia Smirnova, Romain Solinhac, +14

Cardiovascular Research

Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond

Mehul Sharma, Narissara Suratannon, Daniel Leung, +17

Trends in Immunology

Clinical ImmunologyImmunogeneticsAllergyImmune Cell DevelopmentPathogenesis +7