Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy

Azza Abdel-Gadir, Emmanuel Stephen‐Victor, Georg K. Gerber, +15

Nature Medicine

Food AllergyAllergyMicrobial PathogensImmune Cell DevelopmentAllergy Medicine +12

Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial

J. Andrew Bird, Jonathan M. Spergel, Stacie M. Jones, +13

The Journal of Allergy and Clinical Immunology In Practice

Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma

Elena Crestani, Hani Harb, Louis‐Marie Charbonnier, +6

Journal of Allergy and Clinical Immunology

AsthmaFood AllergyEngineeringAllergyAllergy Medicine +12

Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity

Jacob Turner, Emmanuel Stephen‐Victor, Sen Wang, +20

Immunity

AllergyAutoimmune DiseaseAllergy MedicineT-regulatory CellImmune Regulation +8

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

Hani Harb, Mehdi Benamar, Peggy S. Lai, +29

Immunity

InflammationInflammatory Lung DiseaseLung InflammationT-regulatory CellImmunology +6

Dual T cell– and B cell–intrinsic deficiency in humans with biallelic <i>RLTPR</i> mutations

Yi Wang, S. Cindy, Yun Ling, +32

The Journal of Experimental Medicine

A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma

Hani Harb, Emmanuel Stephen‐Victor, Elena Crestani, +14

Nature Immunology

InflammationAsthmaImmune Cell DevelopmentT-regulatory CellImmune Regulation +8

Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma

Wanda Phipatanakul, Petros Koutrakis, Brent A. Coull, +57

JAMA

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

Marita Bosticardo, Yasuhiro Yamazaki, Jennifer E. Cowan, +34

The American Journal of Human Genetics

ImmunogeneticsLymphocyte DevelopmentGeneticsPathogenesisImmunology +7

Exhaled air temperature in asthma: methods and relationship with markers of disease

Giorgio Piacentini, Diego Peroni, Elena Crestani, +4

Clinical & Experimental Allergy