Sahar Kassem

TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma

Camille Guillerey, Heidi Harjunpää, Nadège Carrié et al. · Blood · 2018 · 297 citations · Full text

Life Sciences, Immunology, Oncology +16

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

Kyohei Nakamura, Sahar Kassem, Alice Cleynen et al. · Cancer Cell · 2018 · 221 citations · Full text

Medicine, Immunology, Oncology +15

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Thomas Sécher, Sahar Kassem, Mehdi Benamar et al. · Frontiers in Immunology · 2017 · 142 citations · Full text

Life Sciences, Immunology, Microbiology +17

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

Marianne Weulersse, Assia Asrir, Andrea Pichler et al. · Immunity · 2020 · 139 citations · Full text

Life Sciences, Immunology, Oncology +14

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4 ⁺ T cells

Guillaume Gaud, Romain Roncagalli, Karima Chaoui et al. · Science Signaling · 2018 · 54 citations

Life Sciences, Cell Biology, Immunology +13