Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Whasil Lee, Holly A. Leddy, Yong Chen, +11

Proceedings of the National Academy of Sciences

An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery

Qin Huang, Ken Y. Chan, Jason Wu, +21

Science

Localized force application reveals mechanically sensitive domains of Piezo1

Jason Wu, Raman Goyal, Jörg Grandl

Nature Communications

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

Jason Wu, Michael N. Young, Amanda H. Lewis, +3

Cell Reports

EngineeringLight TouchCytoskeletonMechanotransductionCellular Physiology +18

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

Sairam V. Jabba, Raman Goyal, Jason O. Sosa‐Pagan, +7

Neuron

Knockout MouseMolecular PhysiologySignal TransductionTemperature ActivationSingle-point Mutations +8

A high-efficiency AAV for endothelial cell transduction throughout the central nervous system

Trevor Krolak, Ken Y. Chan, Luke Kaplan, +12

Nature Cardiovascular Research

Endothelial Cell PathobiologyAngiogenesisCell SignalingImmunologyEndothelial Dysfunction +9

Axonal Translation of β-Catenin Regulates Synaptic Vesicle Dynamics

Anne Marion Taylor, Jason Wu, Hwan‐Ching Tai, +1

Journal of Neuroscience

Synaptic TransmissionNeurotransmissionCellular NeurobiologySynaptic SignalingCellular Physiology +16

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B

John Lee, Carl Nist-Lund, Paola Solanes, +5

Hearing Research

Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice

Jason Wu, Paola Solanes, Carl Nist-Lund, +6

Molecular Therapy

Enantioselective Free Radical Allyl Transfers from Allylsilanes Promoted by Chiral Lewis Acids

Ned A. Porter, Jason Wu, Guiru Zhang, +1

The Journal of Organic Chemistry

Allylsilanes PromotedEngineeringRadical (Chemistry)Chiral Lewis AcidsAltmetric Attention Score +8