Jörg Grandl

Piezo proteins are pore-forming subunits of mechanically activated channels

Bertrand Coste, Bailong Xiao, Jose S. Santos et al. · Nature · 2012 · 1.1K citations

Protein Secretion, Molecular Physiology, Signal Transduction +7

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Whasil Lee, Holly A. Leddy, Yong Chen et al. · Proceedings of the National Academy of Sciences · 2014 · 439 citations · Full text

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

Amanda H. Lewis, Jörg Grandl · eLife · 2015 · 402 citations · Full text

Membrane Structure, Engineering, Cytoskeleton +20

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

Jörg Grandl, Sung Eun Kim, Valerie Uzzell et al. · Nature Neuroscience · 2010 · 239 citations · Full text

Pore Domain, Membrane Transport, Trpv1 Ion Channel +7

Pore region of TRPV3 ion channel is specifically required for heat activation

Jörg Grandl, Hongzhen Hu, Michael Bandell et al. · Nature Neuroscience · 2008 · 177 citations

Trpv3 Ion Channel, Engineering, Pore Region +7