Yoshiki Takeoka

Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction

Masaaki Ito, Takashi Yurube, Kenichiro Kakutani et al. · Osteoarthritis and Cartilage · 2017 · 111 citations · Full text

Cell Autophagy, Mtorc1/raptor Protects, Cell Regulation +10

Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the <scp>ORS</scp> spine section

Alon Lai, Jennifer Gansau, Sarah E. Gullbrand et al. · JOR Spine · 2021 · 102 citations · Full text

Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction

Yuji Kakiuchi, Takashi Yurube, Kenichiro Kakutani et al. · Osteoarthritis and Cartilage · 2019 · 80 citations · Full text

Gene Therapy Approach for Intervertebral Disc Degeneration: An Update

Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida · Neurospine · 2020 · 54 citations · Full text

Intervertebral disc cell fate during aging and degeneration: apoptosis, senescence, and autophagy

Takashi Yurube, Yoshiki Takeoka, Yutaro Kanda et al. · North American Spine Society Journal (NASSJ) · 2023 · 40 citations · Full text

Degenerative Spine, Developmental Biology, Aging +8