Takashi Yurube

Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration

Takashi Yurube, Toru Takada, Teppei Suzuki et al. · Arthritis Research & Therapy · 2012 · 121 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction

Masaaki Ito, Takashi Yurube, Kenichiro Kakutani et al. · Osteoarthritis and Cartilage · 2017 · 114 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the <scp>ORS</scp> spine section

Alon Lai, Jennifer Gansau, Sarah E. Gullbrand et al. · JOR Spine · 2021 · 110 citations · Full text

Medicine, Pathology, Diagnostic Assessment +13

Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model

Takashi Yurube, Hiroaki Hirata, Kenichiro Kakutani et al. · Arthritis Research & Therapy · 2014 · 94 citations · Full text

Life Sciences, Cell Biology, Apoptosis +11

Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells

Shingo Miyazaki, Kenichiro Kakutani, Takashi Yurube et al. · Arthritis Research & Therapy · 2015 · 84 citations · Full text

Life Sciences, Cell Biology, Neuroscience +16