Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors

Susanne Trumpp-Kallmeyer, Jan Hoflack, Anne T. Bruinvels, +1

Journal of Medicinal Chemistry

Mammalian Opsin ReceptorsHydropathicity AnalysisHydrophobic StretchesBiochemistryG Protein-coupled Receptor +15

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

David W. Fry, Alexander J. Bridges, William A. Denny, +13

Proceedings of the National Academy of Sciences

Drug TargetCell GrowthChemical BiologyMedicinal ChemistrySignaling Pathway +19

Three-dimensional models of neurotransmitter G-binding protein-coupled receptors.

Marcel Hibert, Susanne Trumpp-Kallmeyer, Anne T. Bruinvels, +1

Molecular Pharmacology

The Binding Site of Neuropeptide Vasopressin V1a Receptor

Bernard Mouillac, Bice Chini, Marie‐Noëlle Balestre, +6

Journal of Biological Chemistry

Avp-binding SiteReceptor Functional DomainsMolecular BiologyBinding SiteHypothalamic Peptide +16

Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.

Bice Chini, Bernard Mouillac, M N Balestre, +6

The EMBO Journal

Molecular PharmacologySignal TransductionMolecular PhysiologyAgonist SelectivityG Protein-coupled Receptor +11

Tyrosine Kinase Inhibitors. 11. Soluble Analogues of Pyrrolo- and Pyrazoloquinazolines as Epidermal Growth Factor Receptor Inhibitors:  Synthesis, Biological Evaluation, and Modeling of the Mode of Binding

Brian D. Palmer, Susanne Trumpp-Kallmeyer, David W. Fry, +3

Journal of Medicinal Chemistry

Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin

Bice Chini, Bernard Mouillac, Marie‐Noëlle Balestre, +7

FEBS Letters

Development of a Binding Model to Protein Tyrosine Kinases for Substituted Pyrido[2,3-<i>d</i>]pyrimidine Inhibitors

Susanne Trumpp-Kallmeyer, John R. Rubin, Christine Humblet, +2

Journal of Medicinal Chemistry

Drug TargetChemical BiologyPharmaceutical ChemistryMolecular PharmacologyMedicinal Chemistry +16

Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.

Carrie Haskell‐Luevano, Tomi K. Sawyer, Susanne Trumpp-Kallmeyer, +4

PubMed

Electron Density FootprintHmc1r ModelMolecular BiologyMelanotropin Peptide AgonistsChemical Biology +18

Design and synthesis of potent, orally active, inhibitors of carboxypeptidase U (TAFIa)

Magnus Polla, Louise Tottie, Carita Nordén, +12

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBiochemistryNatural SciencesMedicineCarboxypeptidase U +4