Marek Kovář

Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes

Onur Boyman, Marek Kovář, Mark P. Rubinstein et al. · Science · 2006 · 860 citations

Adaptive Immune System, T-regulatory Cell, Immunology +18

Converting IL-15 to a superagonist by binding to soluble IL-15Rα

Mark P. Rubinstein, Marek Kovář, Jared F. Purton et al. · Proceedings of the National Academy of Sciences · 2006 · 403 citations · Full text

Inflammation, Cytokine, Molecular Immunology +13

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms

Jamie B. Spangler, Jakub Tomala, Vincent C. Luca et al. · Immunity · 2015 · 214 citations · Full text

Inflammation, Distinct Conformational Mechanisms, Autoimmune Disease +13

Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes

B Řı́hová, Tomáš Etrych, Michal Pechar et al. · Journal of Controlled Release · 2001 · 103 citations

Polymer-drug Conjugate, Medicine, Hydrazone Bond +11

In Vivo Expansion of Activated Naive CD8+ T Cells and NK Cells Driven by Complexes of IL-2 and Anti-IL-2 Monoclonal Antibody As Novel Approach of Cancer Immunotherapy

Jakub Tomala, Helena Chmelova, Tomáš Mrkvan et al. · The Journal of Immunology · 2009 · 100 citations

Immunology, Immunoediting, Anti-il-2 Monoclonal Antibody +18