Crystal structures explain functional properties of two E. coli porins

Sandra W. Cowan, Tilman Schirmer, Gabriele Rummel, +5

Nature

Crystal StructureProtein AssemblyBiochemistryNatural SciencesBiomolecular Structure Prediction +6

X-ray Structure of Bacteriorhodopsin at 2.5 Angstroms from Microcrystals Grown in Lipidic Cubic Phases

Eva Pebay‐Peyroula, Gabriele Rummel, Jürg P. Rosenbusch, +1

Science

X-ray CrystallographyEight Water MoleculesBiochemistryMicrocrystals GrownX-ray Structure +12

Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1

Joseph Schoepfer, Wolfgang Jahnke, Giuliano Berellini, +24

Journal of Medicinal Chemistry

Drug TargetMixed-phenotype Acute LeukemiaMolecular BiologyTumor BiologyMyeloid Neoplasia +14

Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

Sandra W. Cowan‐Jacob, Gabriele Fendrich, Andreas Floersheimer, +7

Acta Crystallographica Section D Biological Crystallography

Imatinib-resistant PatientsMutant Abl KinaseHematological MalignancyStructural Biology ContributionsMedicine +10

Crystal Structure of Osmoporin OmpC from E. coli at 2.0 Å

Arnaud Baslé, Gabriele Rummel, Paola Storici, +2

Journal of Molecular Biology

Crystal StructureE. ColiBiochemistryNatural SciencesProtein X-ray Crystallography +5

The structure of OmpF porin in a tetragonal crystal form

SW Cowan, R. Michael Garavito, J.N. Jansonius, +9

Structure

Materials ScienceCrystal StructureEngineeringStructure ElucidationChemistry +3

Lipidic Cubic Phases: New Matrices for the Three-Dimensional Crystallization of Membrane Proteins

Gabriele Rummel, Ariane Hardmeyer, Christine Widmer, +6

Journal of Structural Biology

Membrane StructureProteinlipid InteractionMembrane FormationEngineeringBiochemistry +10

Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae

Raimund Dutzler, Gabriele Rummel, Sebastián Albertí, +5

Structure

Crystal StructureBiochemistryKlebsiella PneumoniaeProtein X-ray CrystallographyFunctional Characterization +3

Structural and functional alterations of a colicin-resistant mutant of OmpF porin from Escherichia coli.

Denis Jeanteur, Tilman Schirmer, Didier Fourel, +6

Proceedings of the National Academy of Sciences

Proteomic analysis of the bacterial cell cycle

Björn Grünenfelder, Gabriele Rummel, Jiří Vohradský, +3

Proceedings of the National Academy of Sciences