Tom S. Chen - Concepedia

Author

Tom S. Chen

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

T.-Show Chen, TOM S. CHEN, Tom S. Chen

Publications

307

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)Purdue University West Lafayette

About

Tom S. Chen is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in biochemistry, biosynthesis, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	3	3	65
2	Biosynthesis	2	2	42
3	Medicine	1	1	23
4	Pharmacology	1	1	23
5	Drug Discovery	1	1	23

Tom S. Chen

Publications

281

Citations

H-Index

Page 1

	Year	Citations
Use of Near-Infrared Spectroscopy to Evaluate an Active in a Film Coated Tablet B. R. Buchanan, Mark A. Baxter, Tom S. Chen, Pharmaceutical Research	1996	68
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent<i>in vitro</i>and<i>in vivo</i>antitumoral activity which involves DNA damage and ataxia telangiectasia–mutated nuclear protein kinase activation Shin‐Hun Juang, Chia-Chi Lung, Pi-Chen Hsu, Molecular Cancer Therapeutics	2007	65
Further studies on the biosynthesis of the avermectins Tom S. Chen, Byron H. Arison, Vincent P. Gullo, Journal of Industrial Microbiology & Biotechnology	1989	28
Directed biosynthesis of avermectins Tom S. Chen, Edward Inamine, Otto D. Hensens, Archives of Biochemistry and Biophysics BiosynthesisBiotransformationBiochemistryNatural Product BiosynthesisNatural Product Synthesis	1989	24
Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK 506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. Tom S. Chen, Byron H. Arison, Linda S. Wicker, The Journal of Antibiotics	1992	24
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters Sheo B. Singh, John G. Ondeyka, Weiguo Liu, Bioorganic & Medicinal Chemistry Letters OxysterolBiochemistryMedicineLiver PhysiologyExperimental Pharmacology	2005	23
Biotransformation of taxol Tom S. Chen, Xiaohua Li, Dan Bollag, Tetrahedron Letters BiosynthesisBiotransformationBiochemistryNatural Product Biosynthesis	2001	18
Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins). Ali Shafiee, Tom S. Chen, BYRON S. ARISON, The Journal of Antibiotics	1993	17
Microbial hydroxylation and glucuronidation of the angiotensin II(A II) receptor antagonist MK 954. Tom S. Chen, Lie So, Rebecca B. White, The Journal of Antibiotics	1993	14

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