Otto D. Hensens

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Mevinolinic Acid, Pharmaceutical Science, Medicinal Fungi +19

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

Daniel M. Bollag, Patricia A. McQueney, Jian‐Yong Zhu et al. · PubMed · 1995 · 686 citations

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

James D. Bergstrom, Marc M. Kurtz, Deborah J. Rew et al. · Proceedings of the National Academy of Sciences · 1993 · 334 citations · Full text

Biosynthesis, Natural Product Synthesis, Biochemistry +9

A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus

Ray Chang, Virginia Lotti, Richard L. Monaghan et al. · Science · 1985 · 320 citations

Gastrointestinal Pharmacology, Antibiotic Adjuvant, Immunology +18

Structure and absolute configuration of thienamycin

G. ALBERS‐SCHOENBERG, Byron H. Arison, Otto D. Hensens et al. · Journal of the American Chemical Society · 1978 · 299 citations

Chemical Measurement, Absolute Configuration, Engineering +14