John H. Van Drie

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 813 citations · Full text

Lineage-specific Tumours, Medicine, Immune Checkpoint Inhibitor +8

Computer-aided drug design: the next 20 years

John H. Van Drie · Journal of Computer-Aided Molecular Design · 2007 · 205 citations

Medicinal Chemistry, Drug Design, Medicine +9

ALADDIN: An integrated tool for computer-assisted molecular design and pharmacophore recognition from geometric, steric, and substructure searching of three-dimensional molecular structures

John H. Van Drie, David Weininger, Yvonne C. Martin · Journal of Computer-Aided Molecular Design · 1989 · 189 citations

Engineering, Biochemistry, Medicine +13

Assessing How Well a Modeling Protocol Captures a Structure−Activity Landscape

Rajarshi Guha, John H. Van Drie · Journal of Chemical Information and Modeling · 2008 · 83 citations

Engineering, Modeling Method, Structure-activity Relationship Pairwise +20

Approaches to virtual library design

John H. Van Drie, Michael S. Lajiness · Drug Discovery Today · 1998 · 77 citations

Architectural Design, Library Design, Engineering +9