Andrew M. K. Pennell

Characterization of CCX282-B, an Orally Bioavailable Antagonist of the CCR9 Chemokine Receptor, for Treatment of Inflammatory Bowel Disease

Matthew J. Walters, Yu Wang, Trageen Baumgart et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 159 citations

Life Sciences, Immunology, Pharmacology +17

A novel route to biaryls via intramolecular free radical ipso substitution reactions

William B. Motherwell, Andrew M. K. Pennell · Journal of the Chemical Society Chemical Communications · 1991 · 143 citations

Natural Sciences, Chemistry, Drug Discovery +11

The Nitro-Mannich Reaction and Its Application to the Stereoselective Synthesis of 1,2-Diamines

Harry Adams, James C. Anderson, Simon Peace et al. · The Journal of Organic Chemistry · 1998 · 116 citations

Natural Sciences, Chemistry, Catalysis +10

CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice

Timothy J. Sullivan, Zhenhua Miao, Daniel J. Dairaghi et al. · American Journal of Physiology-Renal Physiology · 2013 · 88 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Design and Synthesis of Pyrrolidine-5,5-<i>trans-</i>lactams (5-Oxohexahydropyrrolo[3,2-<i>b</i>]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and Chirality

Alan D. Borthwick, Andrew J. Crame, Peter Ertl et al. · Journal of Medicinal Chemistry · 2001 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16