Wa Du

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function

Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui et al. · Nature Medicine · 2012 · 200 citations · Full text

Endothelial Cell Pathobiology, Signal Transduction, Developmental Biology +11

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

Noriko Takuwa, Sei-Ichiro Ohkura, S Takashima et al. · Cardiovascular Research · 2009 · 143 citations · Full text

S1P2, the G Protein–Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth <i>In vivo</i> in Mice

Wa Du, Noriko Takuwa, Kazuaki Yoshioka et al. · Cancer Research · 2010 · 113 citations · Full text

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

Fei Wang, Yasuo Okamoto, Isao Inoki et al. · Journal of Clinical Investigation · 2010 · 78 citations · Full text

Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde.

Noriko Takuwa, Wa Du, Erika Kaneko et al. · PubMed · 2011 · 58 citations · Full text

Immunology, Tumor-promoting Sphingosine-1-phosphate Receptor-1, Cancer Biology +18