Concepedia

Publication | Open Access

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

DOIFull Paper Access

143

Citations

24

References

2009

Year

Noriko Takuwa, Sei-Ichiro Ohkura, S Takashima, Keisuke Ohtani, Yasuo Okamoto, Tamotsu Tanaka, Kaoru Hirano, Soichiro Usui, Fei Wang, Wa Du,
Cardiovascular Research

Abstract

These results suggest that chronic activation of SPHK1-S1P signalling results in both pathological cardiac remodelling through ROS mediated by S1P3 and favourable cardioprotective effects.

References

YearCitations

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