Nidhal Selmi

Discovery of a Potent, Selective, and Orally Bioavailable Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor: Discovery of 2-[(3<i>S</i>)-1-[5-(Cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic Acid (AZD4017)

James S. Scott, Suzanne S. Bowker, Joanne deSchoolmeester et al. · Journal of Medicinal Chemistry · 2012 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-<i>tert</i>-butyl-pyrazol-1-yl]benzoic Acid (AZD8329)

James S. Scott, Joanne deSchoolmeester, Elaine Kilgour et al. · Journal of Medicinal Chemistry · 2012 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of AZD2716: A Novel Secreted Phospholipase A₂ (sPLA₂) Inhibitor for the Treatment of Coronary Artery Disease

Fabrizio Giordanetto, Daniel Pettersen, Ingemar Starke et al. · ACS Medicinal Chemistry Letters · 2016 · 42 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

“Ring Breaker”: Neural Network Driven Synthesis Prediction of the Ring System Chemical Space

Amol Thakkar, Nidhal Selmi, Jean‐Louis Reymond et al. · Journal of Medicinal Chemistry · 2020 · 37 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis

Tian Xia, Gregory S. Basarab, Nidhal Selmi et al. · MedChemComm · 2016 · 30 citations

Engineering, Biochemistry, Biotechnology +12