The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages

Kyle C. Cady, Joe Bondy-Denomy, Gary E. Heussler, +2

Journal of Bacteriology

EngineeringBacteriophageMolecular BiologyCrispr Spacer RnaGenome Engineering +17

Interaction between Bacteriophage DMS3 and Host CRISPR Region Inhibits Group Behaviors of<i>Pseudomonas aeruginosa</i>

Michael E. Zegans, Jeffrey C. Wagner, Kyle C. Cady, +3

Journal of Bacteriology

Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa

Alex van Belkum, Leah Soriaga, Matthew C. LaFave, +18

mBio

Non-Identity-Mediated CRISPR-Bacteriophage Interaction Mediated via the Csy and Cas3 Proteins

Kyle C. Cady, George A. O’Toole

Journal of Bacteriology

EngineeringBacteriophageMolecular BiologyCrispr System FunctionCrispr +15

Unsupervised Extraction of Stable Expression Signatures from Public Compendia with an Ensemble of Neural Networks

Jie Tan, Georgia Doing, Kimberley A. Lewis, +7

Cell Systems

Artificial IntelligenceCross-experiment ComparisonsMachine LearningEngineeringMachine Learning Tool +24

Prevalence, conservation and functional analysis of Yersinia and Escherichia CRISPR regions in clinical Pseudomonas aeruginosa isolates

Kyle C. Cady, Arieanna White, John H. Hammond, +5

Microbiology

Microbial PathogensFunctional AnalysisBacterial PathogensCrisprInfection Control +14

Mucin Glycans Signal through the Sensor Kinase RetS to Inhibit Virulence-Associated Traits in Pseudomonas aeruginosa

Benjamin Wang, Kelsey M. Wheeler, Kyle C. Cady, +4

Current Biology

Antimicrobial Resistance GeneMucin Glycans SignalVirulence FactorBacteriologySensor Kinase Rets +7

Correlation between phenotypic antibiotic susceptibility and the resistome in Pseudomonas aeruginosa

Magali Jaillard, Alex van Belkum, Kyle C. Cady, +12

International Journal of Antimicrobial Agents

Antimicrobial Resistance GeneAntimicrobial SusceptibilityHealth SciencesAntibioticsPhenotypic Antibiotic Susceptibility +8

Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas aeruginosa Mediated by Increased Expression of Phage-Related Genes

Gary E. Heussler, Kyle C. Cady, Katja Koeppen, +3

mBio

Cloning, Assembly, and Modification of the Primary Human Cytomegalovirus Isolate Toledo by Yeast-Based Transformation-Associated Recombination

Sanjay Vashee, Timothy B. Stockwell, Nina Alperovich, +11

mSphere