Ken‐ichi Nunoya

A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3 -pyridyl)thiazolidin-4-one hydrochloride (SM-12502)

Ken‐ichi Nunoya, Tsuyoshi Yokoi, Kanzo Kimura et al. · Pharmacogenetics · 1998 · 112 citations

Medicine, Biochemistry, Pharmacology +16

A New CYP2A6 Gene Deletion Responsible for the In Vivo Polymorphic Metabolism of (+)-cis-3,5-Dimethyl-2-(3-pyridyl)thiazolidin-4-one Hydrochloride in Humans

Ken‐ichi Nunoya, Tsuyoshi Yokoi, Kanzo Kimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 101 citations

Medicine, Molecular Genetics, Pharmacology +13

Genetic polymorphism of CYP2A6 in relation to cancer

Tetsuya Kamataki, Ken‐ichi Nunoya, Yuki Sakai et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 1999 · 85 citations

Medicine, Genetics, Oncology +10

Homologous Unequal Cross-Over within the Human CYP2A Gene Cluster as a Mechanism for the Deletion of the Entire CYP2A6 Gene Associated with the Poor Metabolizer Phenotype

Ken‐ichi Nunoya, Tsuyoshi Yokoi, Yuki Takahashi et al. · The Journal of Biochemistry · 1999 · 68 citations

Medicine, Genetics, Molecular Genetics +6

A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies

Ryo Ito, Kenta Umehara, Shota Suzuki et al. · Molecular Pharmaceutics · 2019 · 62 citations

Pharmacy, Neuroscience, Pharmacology +16