Felix A. Dingler

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Guillermo Burgos-Barragan, Niek J. de Wit, Johannes Meiser et al. · Nature · 2017 · 356 citations · Full text

One-carbon Metabolism, Biochemistry, Carbonyl Metabolism +4

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis

Bidesh Mahata, Xiuwei Zhang, Aleksandra A. Kolodziejczyk et al. · Cell Reports · 2014 · 228 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +21

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

Felix A. Dingler, Meng Wang, Anfeng Mu et al. · Molecular Cell · 2020 · 176 citations · Full text

Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response

Lee Mulderrig, Juan I. Garaycoechea, Zewen Kelvin Tuong et al. · Nature · 2021 · 133 citations · Full text

Genome Instability, Transcriptional Regulation, Dna Damage +7

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung−/−Msh2−/− mice

Kristin Kemmerich, Felix A. Dingler, Cristina Rada et al. · Nucleic Acids Research · 2012 · 105 citations · Full text

Epigenetic Change, Genetics, Molecular Biology +20