I.J. Clifton

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian et al. · EMBO Reports · 2011 · 1K citations · Full text

Histone Modifications, Chromatin, Biochemistry +6

Structure of isopenicillinN synthase complexed with substrate and the mechanism ofpenicillin formation

Peter L. Roach, I.J. Clifton, Charles M. H. Hensgens et al. · Nature · 1997 · 429 citations

Mechanism Ofpenicillin Formation, Biotransformation, Isopenicillinn Synthase Complexed +7

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

Peter L. Roach, I.J. Clifton, Vilmos Fülöp et al. · Nature · 1995 · 415 citations

Crystal Structure, Biochemistry, Isopenicillin N Synthase +8

Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis thaliana

R.C. Wilmouth, Jonathan J. Turnbull, Richard W.D. Welford et al. · Structure · 2002 · 365 citations · Full text

Biosynthesis, Biochemistry, Natural Sciences +4

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

M.A. McDonough, Vivian Li, Emily Flashman et al. · Proceedings of the National Academy of Sciences · 2006 · 365 citations · Full text

Redox Signaling, Crystal Structure, Transcriptional Regulation +14