Online chemical modeling environment (OCHEM): web platform for data storage, model development and publishing of chemical information

Iurii Sushko, Sergii Novotarskyi, Robert Körner, +29

Journal of Computer-Aided Molecular Design

EngineeringChemical AnalysisQsar ModelingOchem DatabaseChemistry +24

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, +31

Cell

The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

Lara Planas‐Paz, Vanessa Orsini, Luke Boulter, +30

Nature Cell Biology

Molecular PhysiologyHepatologyLiver PhysiologyRspo–lgr4/5–znrf3/rnf43 Module ControlsHepatotoxicity +5

Why Are Some Properties More Difficult To Predict than Others? A Study of QSPR Models of Solubility, Melting Point, and Log P

Laura D. Hughes, David Scott Palmer, Florian Nigsch, +1

Journal of Chemical Information and Modeling

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

Lara Planas‐Paz, Tianliang Sun, Monika Pikiolek, +36

Cell stem cell

Signal TransductionDevelopmental BiologyHepatologyLiver InjuryBiliary Epithelial Cells +12

Melting Point Prediction Employing <i>k</i>-Nearest Neighbor Algorithms and Genetic Parameter Optimization

Florian Nigsch, Andreas Bender, Bernd N. M. van Buuren, +3

Journal of Chemical Information and Modeling

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions

Dominic Hoepfner, Stephen B. Helliwell, Heather Sadlish, +32

Microbiological Research

Prokaryotic SystemProtein AssemblyStructural BioinformaticsProtein FoldingNatural Sciences +9

Rethinking Molecular Similarity: Comparing Compounds on the Basis of Biological Activity

Paula Petrone, B. T. Simms, Florian Nigsch, +7

ACS Chemical Biology

Ligand-Target Prediction Using Winnow and Naive Bayesian Algorithms and the Implications of Overall Performance Statistics

Florian Nigsch, Andreas Bender, Jeremy L. Jenkins, +1

Journal of Chemical Information and Modeling

Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia

Caroline Dafflon, Vanessa J. Craig, Hélène Méreau, +17

Leukemia

Hematological MalignancyMedicineMixed-phenotype Acute LeukemiaMalignant Blood DisorderComplementary Activities +6