Concepedia

Mark Rolfe

MR

41

Publications

9.3K

Citations

32

H-Index

1995

Active since

Affiliations

Millennium Engineering and Integration (United States)(Current)

Bristol-Myers Squibb (United States)

Harvard University

Albany Medical Center Hospital

Aptose Biosciences (United States)

Mark Rolfe is an author at Millennium Engineering and Integration (United States) specializing in medicine, cell biology, and tumor biology.

Top concepts

MedicineCell BiologyTumor BiologyCancer ResearchNatural SciencesPharmacologyMolecular BiologyOncologyBiochemistryCancer Biology

Publications per year

1995–2021

41

Publications

41

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

Novel Therapy, Medicine, New Approach +9

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

Michele Pagano, Sun W. Tam, Anne M. Theodoras et al. · Science · 1995 · 1.8K citations

Protein Function, Cell Regulation, Ubiquitin-proteasome Pathway +15

A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

Randall W. King, Jan‐Michael Peters, Stuart Tugendreich et al. · Cell · 1995 · 964 citations · Full text

Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer

Erik Kupperman, Edmund C. Lee, Yueying Cao et al. · Cancer Research · 2010 · 488 citations

Proteasome Inhibitor Mln9708, Antitumor Activity, Immunology +21

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

James E. Brownell, Michael D. Sintchak, James M. Gavin et al. · Molecular Cell · 2010 · 457 citations · Full text

Protein Chemistry, Nedd8-amp Mimetic, Protein Function +7

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