Dorothy Zakula

‘Seed’ analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737

Xiaoyu Lin, Susan E. Morgan-Lappe, Xiaoli Huang et al. · Oncogene · 2006 · 228 citations

‘ Seed, Tumor Biology, Off-target Sirnas Reveals +9

Identification of Ras-Related Nuclear Protein, Targeting Protein for <i>Xenopus</i> Kinesin-like Protein 2, and Stearoyl-CoA Desaturase 1 as Promising Cancer Targets from an RNAi-Based Screen

Susan E. Morgan-Lappe, Lora A. Tucker, Xiaoli Huang et al. · Cancer Research · 2007 · 129 citations

Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Steven W. Muchmore, Jun Chen, Clarissa G. Jakob et al. · Molecular Cell · 2000 · 126 citations

Crystal Structure, Biochemistry, Natural Sciences +7

Kinetics of β‐1,3 Glucan Interaction at the Donor and Acceptor Sites of the Fungal Glucosyltransferase Encoded by the <i>BGL2</i> Gene

Robert C. Goldman, Patrick A. Sullivan, Dorothy Zakula et al. · European Journal of Biochemistry · 1995 · 99 citations

Engineering, Fungal Cell Biology, Cell Wall Structure +16

Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells

Aparna V. Sarthy, Susan E. Morgan-Lappe, Dorothy Zakula et al. · Molecular Cancer Therapeutics · 2007 · 77 citations · Full text

Immunology, Cell Death, Cell Proliferation +19