Ann-Sofie Sandinge

Structural and functional characterization of a specific antidote for ticagrelor

Andrew Buchanan, Philip M. Newton, S. KENNETH PEHRSSON et al. · Blood · 2015 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein

Nigel Davies, Daniel Hovdal, Nicholas J. Edmunds et al. · Molecular Therapy — Nucleic Acids · 2021 · 89 citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates

Kurt L. Harris, Raine E. S. Thomson, Yosephine Gumulya et al. · Molecular Biology and Evolution · 2022 · 32 citations · Full text

Medicine, Biology, Evolutionary Biology +17

Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin

S. KENNETH PEHRSSON, K. J Johansson, Annika Janefeldt et al. · Journal of Thrombosis and Haemostasis · 2017 · 27 citations · Full text

Medicine, Hematology, Pharmacology +5

Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans

Chandrali Bhattacharya, Ann-Sofie Sandinge, Ryan A. Bragg et al. · Drug Metabolism and Disposition · 2023 · 12 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17