Nicholas J. Edmunds

Extracellular vesicles induce minimal hepatotoxicity and immunogenicity

Amer F. Saleh, Elisa Lázaro‐Ibáñez, M. Forsgard et al. · Nanoscale · 2019 · 192 citations

Pharmacy, Cell Biology, Toxicology +17

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein

Nigel Davies, Daniel Hovdal, Nicholas J. Edmunds et al. · Molecular Therapy — Nucleic Acids · 2021 · 89 citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium

Markus Wallner, Ewald Kolesnik, Klemens Ablasser et al. · Journal of Molecular and Cellular Cardiology · 2015 · 63 citations

Medicine, Cardiology, Pharmacology +13

Cardiovascular safety assessments in the conscious telemetered dog: Utilisation of super-intervals to enhance statistical power

A. Sivarajah, Susie M. Collins, Mike Sutton et al. · Journal of Pharmacological and Toxicological Methods · 2010 · 53 citations

Medicine, Cardiology, Veterinary Physiology +12

Effects of tumour necrosis factor‐α on left ventricular function in the rat isolated perfused heart: possible mechanisms for a decline in cardiac function

Nicholas J. Edmunds, H. Lal, Brian Woodward · British Journal of Pharmacology · 1999 · 51 citations · Full text

Medicine, Pharmacology, Physiology +10