Jeffrey Chiang

Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms

Jie Lu, John S. Kovach, Francis Johnson et al. · Proceedings of the National Academy of Sciences · 2009 · 161 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

Jie Lu, Jason M Frerich, L. Christine Turtzo et al. · Proceedings of the National Academy of Sciences · 2013 · 88 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Telomere Protection Mechanisms Change during Neurogenesis and Neuronal Maturation: Newly Generated Neurons Are Hypersensitive to Telomere and DNA Damage

Aiwu Cheng, Kazuo Shin‐ya, Ruiqian Wan et al. · Journal of Neuroscience · 2007 · 77 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl

Jie Lu, Jeffrey Chiang, Rajiv R. Iyer et al. · Proceedings of the National Academy of Sciences · 2010 · 47 citations · Full text

Life Sciences, Biochemistry, Genetics +17

Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy

Lucia Martiniova, Jie Lu, Jeffrey Chiang et al. · PLoS ONE · 2011 · 36 citations · Full text

Medicine, Oncology, Pharmacology +16