Tetsuya Okada

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

Kyung‐Ho Lee, Witoon Tirasophon, Xiaohua Shen et al. · Genes & Development · 2002 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1

Keisuke Yamamoto, Takashi Sato, Toshie Matsui et al. · Developmental Cell · 2007 · 1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the<i>cis</i>-Acting Element Responsible for the Mammalian Unfolded Protein Response

Hiderou Yoshida, Tetsuya Okada, Kyosuke Haze et al. · Molecular and Cellular Biology · 2000 · 936 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

Masahiro Shuda, Nobuo Kondoh, Nobuo Imazeki et al. · Journal of Hepatology · 2003 · 515 citations

Medicine, Molecular Biology, Oncology +13