Combination therapy with anti-HIV-1 antibodies maintains viral suppression

Pilar Mendoza, Henning Gruell, Lilian Nogueira, +33

Nature

Human RetrovirusImmunologyAntiviral TherapyAntiviral ResponseVirology +4

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Marina Caskey, Till Schoofs, Henning Gruell, +34

Nature Medicine

Hiv-1-infected IndividualsHuman RetrovirusImmunologyAntiviral ResponseVirology +5

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

Johannes F. Scheid, Joshua A. Horwitz, Yotam Bar‐On, +30

Nature

Viral PersistenceHuman RetrovirusImmunologyAntiviral ResponseAntiviral Therapy +8

Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals

Yotam Bar‐On, Henning Gruell, Till Schoofs, +30

Nature Medicine

Viremic IndividualsAntiviral ActivityHuman RetrovirusImmunologyAntiviral Response +8

Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

Julio C. C. Lorenzi, Yehuda Z. Cohen, Lillian B. Cohn, +13

Proceedings of the National Academy of Sciences

Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity

Julia Niessl, Amy E. Baxter, Pilar Mendoza, +11

Nature Medicine

Human RetrovirusImmunologyAntiviral TherapyAntiviral ResponseAutoimmunity +6

Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation

Lillian B. Cohn, Israel Tojal da Silva, Renan Valieris, +8

Nature Medicine

Human RetrovirusT-regulatory CellHiv-1 Latent ReservoirImmunologyAntiviral Response +8

Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117

Yehuda Z. Cohen, Julio C. C. Lorenzi, Lisa Krassnig, +18

The Journal of Experimental Medicine

Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study

Yehuda Z. Cohen, Allison L. Butler, Katrina G. Millard, +23

PLoS ONE

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention

Lindsey R. Baden, Etienne Karita, Gaudensia Mutua, +28

Annals of Internal Medicine